Biochemical and molecular modulation of CCl 4 -induced peripheral and central damage by Tilia americana var. mexicana extracts

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Biochemical and molecular modulation of CCl4-induced peripheral and central damage by Tilia americana var. mexicanaextracts.

Around the world, species from the genus Tilia are commonly used because of their peripheral and central medicinal effects; they are prepared as teas and used as tranquilizing, anticonvulsant, and analgesic agents. In this study, we provide evidence of the protective effects of organic and aqueous extracts (100 mg/kg, i.p.) obtained from the leaves of Tilia americana var. mexicana on CCl4-induc...

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Anxiolytic and sedative-like effects of flavonoids from Tilia americana var. mexicana: GABAergic and serotonergic participation

Introduction The inflorescences of Tilia americana var. mexicana are used as an infusion in Mexican traditional medicine due to their tranquilizing effects; however, pharmacological and phytochemical studies of the leaves are lacking. Objective In this research, the anxiolytic and sedative-like efficacy of the Tilia americana var. mexicana leaves was compared to that obtained with its infloresc...

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Anticonvulsant and Antioxidant Effects of Tilia americana var. mexicana and Flavonoids Constituents in the Pentylenetetrazole-Induced Seizures

Tilia genus is commonly used around the world for its central nervous system properties; it is prepared as tea and used as tranquilizing, anticonvulsant, and analgesic. In this study, anticonvulsant activity of the Tilia americana var. mexicana inflorescences and leaves was investigated by evaluating organic and aqueous extracts (100, 300, and 600 mg/kg, i.p.) and some flavonoids in the pentyle...

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Mitosis in Tilia americana endosperm

The endosperm cells of the American basswood Tilia americana are favorable experimental material for investigating the birefringence of living plant spindles and anaphase movement of chromosomes. The behavior of the chromosomes in anaphase and the formation of the phragmoplast are unique. The numerous (3 n equals 123), small chromosomes move in precise, parallel rows until midanaphase when they...

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Modulation of radiation and cadmium induced biochemical changes in mouse kidney by Emblica officinalis Linn

Background: Protective effect of Emblica against radiation and cadmium induced biochemical changes in mouse kidney has been studied. Materials and Methods: Adult male mice were divided into seven groups: I (shamirradiated), II (cadmium chloride), III (irradiated with 2 Gy gamma rays), IV (radiation and cadmium chloride), V (Cadmium chloride and Emblica), VI (radiation and Emblica), VII...

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ژورنال

عنوان ژورنال: Saudi Pharmaceutical Journal

سال: 2017

ISSN: 1319-0164

DOI: 10.1016/j.jsps.2016.06.008